The I-neb® Adaptive Aerosol Delivery (AAD®) System is a battery-powered pulmonary drug delivery system that makes it possible for patients to take their VENTAVIS® (iloprost) Inhalation Solution treatments almost anywhere. With up to 40 treatments from a single charge, the I-neb AAD System frees patients from the need to be near an electrical outlet. The Adaptive Aerosol Delivery (AAD) technology is designed to help patients receive a more accurate dose.23
VENTAVIS is a prostacyclin analogue with a narrow therapeutic index. The AAD was designed to help provide more precise and reproducible dosing of VENTAVIS to every patient, required for the safety and efficacy of the drug.
The system uses AAD technology to precisely and reproducibly deliver VENTAVIS to every patient, at either dose (2.5 mcg or 5.0 mcg), using a single ampule of medication.2 The dose each patient receives is controlled by the medication chamber. The I-neb AAD System continuously monitors and analyzes a patient's breathing pattern and delivers pulses of aerosol into the start of each inhalation until the set dose is delivered.
Standard air-jet nebulizers/compressors or ultrasonic nebulizer systems are continuous flow systems that constantly generate aerosol. Patients typically have a 40:60 inhalation:exhalation ratio; therefore, about 60% of the drug is wasted to the environment with such devices during exhalation.2 Additionally, a variable amount of drug is inhaled by each patient because individual breathing patterns differ (e.g., short, shallow breaths to long, deep breaths).
With the I-neb AAD System there is no need for complex assembly or disassembly. There is no daily, weekly, or monthly scheduled part replacement. The chamber lid's mesh replacement is scheduled by your specialty pharmacy. And no more than daily cleaning and a weekly boil are required.
The I-neb AAD learns your patient's specific breathing pattern through smart technology by Philips Respironics. It adapts to the individual for accurate and consistent delivery of the prescribed dose to help your patient get the full dose of medicine.
Only one drug treatment (either 2.5 mcg or 5.0 mcg) can be delivered from the contents of a single ampule. Reuse of any drug solution that remains after completing a drug treatment, even if the reservoir is "topped off" with fresh medication, will not give accurate dosing. Do not reuse ampules.
The I-neb AAD System is fully portable so patients may take their treatments almost anywhere. It is lightweight and small enough to fit into a purse or jacket pocket, and with 40 uses per battery charge patients can feel comfortable taking their treatments with them wherever they go.